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Caption:
Methylotrophic yeast (Pichia pastoris). This methylotrophic yeast was isolated from nature and can consume methanol as a sole carbon source when glycerol or glucose is not found as a food source. It is a recombinant organism that is used to produce large quantities of specialized proteins. To metabolize methanol Pichia pastoris has an alcohol oxidase (AOX) gene. The P. pastoris expression system uses the methanol-induced alcohol oxidase promoter (AOX1) which controls the gene that codes for the expression of alcohol oxidase (the enzyme which catalyzes the fist step in the metabolism of methanol). Using genetic techniques genes for pharmaceutical proteins can be inserted next to the AOX-gene in Pichia allowing the yeast to produce the protein. A number of proteins have been produced using this system, including tetanus toxin fragment, Bordatella pertussus petactin, human serum albumin and lysozyme.
Keywords:
| 23710C 06.01.04 alcohol oxidase benchtop fermentation bud bud scar bud scars budding eukaryote eukaryotic expression fungi fungi and slime molds fungus gene expression genetic recombination methanol fermentation methylotrophic yeast Pichia pastoris protein expression recombinant organism recombinant yeast yeast yeast bud yeast budding SEM |
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Dennis Kunkel Microscopy, Inc. is a scientific stock photography agency (science stock photography, science stock photographs / pictures) featuring biology, medical and biomedical microscopy photos / pictures taken with light microscopes (LM) and electron microscopes (transmission electron microscope - TEM; scanning electron microscope - SEM). Microscopy photographs (science images, electron microscope images, photomicrographs, microscopy photos, microscope photos, microscopic pictures) are available for use in editorial and commercial formats. Image categories include Algae, Arachnids, Bacteria, Crystals, Fungi, Insects, Invertebrates, Medical, Miscellaneous, Plants, Protozoa, Vertebrates and Viruses.
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